Immunology Faculty

Jeffrey Bender

Robert I. Levy Professor of Medicine (Cardiology) and Professor of Immunobiology
Associate Chief, Cardiovascular Medicine

Research Interests:Inflammatory, Immune, Metabolic and Hormonal Effects on the Endothelium

Alfred Bothwell

Professor of Immunobiology
Director of Graduate Studies

Research Interests:Human T cell recognition; inflammation and cancer; type 1 diabetes; function of PPARs

United Technologies Corporation Professor in Cancer Research and Professor of Immunobiology, of Dermatology and of Medicine (Medical Oncology)
Director, Cancer Immunology Program at Yale Cancer Center

Research Interests:Co-signaling molecules, costimulation, coinhibition, modulation of immune responses, molecular mechanisms of lymphocyte activation and deactivation

Tian Chi

Associate Professor of Immunobiology

Research Interests:Epigenetic memory; transgenerational inheritance; chromatin biology

Joseph Craft

Paul B. Beeson Professor of Medicine (Rheumatology) and Professor of Immunobiology
Section Chief, Rheumatology
Program Director, Investigative Medicine
Paul B. Beeson Professor of Medicine

Research Interests:Arthritis; Autoimmunity; Cytokines; Diseases and Disorders; Lupus; T Cell Differentiation; T Cells; Tolerance

Peter Cresswell

Eugene Higgins Professor of Immunobiology and Professor of Cell Biology and of Dermatology

Research Interests:Molecular mechanisms of antigen processing; assembly and intracellular transport of CD1 molecules, class I and class II MHC molecules; effector functions and mechanisms of action of interferon-induced proteins; viral immunity

Madhav Dhodapkar

Arthur H. and Isabel Bunker Professor of Medicine (Hematology) and Professor of Immunobiology
Chief, Section of Hematology, Department of Internal Medicine
Clinical Research Program Leader, Hematology Program, Yale Cancer Center

Research Interests:Myeloma and related plasma cell disorders; human immune system's interaction with growing tumors in patients; preneoplastic monoclonal gammopathy and multiple myeloma, tumor and host related factors

Jack Elias

Waldemar Von Zedtwitz Professor of Medicine and Professor of Immunobiology
Chair, Department of Internal Medicine

Research Interests:Cell and Molecular biology of lung injury and repair; Asthma; COPD; Pulmonary fibrosis; acute lung injury; Cytokines; Inflammation; Internal Medicine; Pulmonary Diseases; Transgenic mice; genetically modified mice; Emphysema; Fibrosis; Inflammation

Erol Fikrig

Waldemar Von Zedtwitz Professor of Medicine (Infectious Diseases) and Professor of Epidemiology (Microbial Diseases) and of Microbial Pathogenesis
Investigator, Howard Hughes Medical Institute
Section Chief, Infectious Diseases

Research Interests:Vector-borne diseases; Lyme disease; Human granulocytic ehrilichiosis; West Nile virus

Richard Flavell

Sterling Professor of Immunobiology
Investigator, Howard Hughes Medical Institute
Department Chair, Immunobiology

Research Interests:Animal Models; Autoimmunity; Diabetes; Gene Expression; Gene Transfer; Genes; Immune System; Lyme Borreliosis Or Lyme Disease; Molecular Cellular Entities; Recombinant DNA; Transgenic Animals; Autoimmunity; Knockout Mice; Lyme Disease; T Cell Lineages; Tolerance; Transgenic Mice

Daniel Goldstein

Associate Professor of Medicine (Cardiology) and of Immunobiology

Research Interests:immunity in transplantation; impact of aging on inflammation and immunity

David Hafler

Gilbert H. Glaser Professor of Neurology and Professor of Immunobiology
Chair, Department of Neurology

Research Interests:Neuroimmunology; Multiple Sclerosis; Autoimmunity; Genetics; Immunobiology

Kevan Herold

Professor of Immunobiology and of Medicine (Endocrinology)
Deputy Director for Translational Science, YCCI

Research Interests:Type 1 diabetes; immune therapy; autoimmunity

Akiko Iwasaki

Professor of Immunobiology and of Molecular, Cellular, and Developmental Biology
Professor of Molecular Cellular and Developmental Biology
Howard Hughes Medical Investigator

Research Interests:Innate immunity; Autophagy; Inflammasomes; sexually transmitted infections; Herpes simplex virus; human papillomavirus;respiratory virus infections; Influenza infection; T cell immunity; Commensal bacteria

Susan Kaech

Associate Professor of Immunobiology
HHMI Early Career Scientist

Research Interests:Mechanisms of memory T cell development; Developmental Biology; Immunobiology; Immunology; Vaccine; Immunobiology; T-Cells; Vaccines; Adaptive immunity and immunological memory to viruses

Paula Kavathas

Professor of Laboratory Medicine, of Genetics, of Immunobiology and of Molecular, Cellular, and Developmental Biology
Associate Chair for Research
Director, Science Education Outreach Program

Research Interests:Gene Regulation; Immunology; Molecular Cellular Entities; Receptors; Structure or Function (Health or Safety or Medical); Transgenic Animals

Steven Kleinstein

Associate Professor of Pathology

Research Interests:Computational immunology; Systems biology; Disease/tissue/pathway/process modeling and simulation; Statistical and model-based analysis of experimental and clinical data

Martin Kriegel

Assistant Professor of Immunobiology and of Medicine (Rheumatology)
Assistant Professor of Medicine (Rheumatology)

Research Interests:Microbiome; commensals; lymphocytes; autoimmunity; Th17 cells; antiphospholipid syndrome; beta2-glycoprotein; lupus; type 1 diabetes

Priti Kumar

Assistant Professor of Medicine (Infectious Diseases) and of Microbial Pathogenesis

Research Interests:RNA interference (RNAi)-based strategies for treating viral infections

Brett Lindenbach

Associate Professor of Microbial Pathogenesis

Research Interests:Cell Biology; Enveloped Viruses; Hepatitis; Hepatitis C Virus; Molecular Biology; Positive-strand RNA Viruses; RNA; Virology; Virus

Robert Means

Associate Professor of Pathology
Director of Graduate Admissions, Microbiology Program

Research Interests:Viruses; Immune responses; AIDS-associated cancers; KSHV; Adverse pregnancy events; Oncogenesis; Cancer metabolism; Tumor virology; Herpesviruses

Ruslan Medzhitov

David W. Wallace Professor of Immunobiology
Investigator, Howard Hughes Medical Institute

Research Interests:Inflammation; Allergy; Immunology; Innate Immunity; Pathophysiology

Eric Meffre

Associate Professor of Immunobiology and of Medicine (Immunology)

Research Interests:Human B-cell tolerance; Primary immunodeficiencies; Autoimmune diseases

Wang Min

Associate Professor of Pathology

Research Interests:Inflammation; Angiogenesis; Atherosclerosis; Transplant rejection; Tumor metastasis

João Pereira

Assistant Professor of Immunobiology

Research Interests:Immunology; Hematopoiesis; B-lymphocyte development; Bone marrow niches; Cell migration

Jordan Pober

Bayer Professor of Immunobiology and Professor of Dermatology and of Pathology
Director, Human and Translational Immunology Program
Vice-Chair, Dept. of Immunobiology for the Section of Human and Translational Immunology

Research Interests:Immunobiology of vascular endothelial cells: cytokine actions and mechanisms; transplantation immunology

Carla Rothlin

Assistant Professor of Immunobiology

Research Interests:Regulation of inflammation; homeostatic control of the immune system

Craig Roy

Professor of Microbial Pathogenesis

Research Interests:Molecular; cellular; microbial pathogens; bacteria; vesicular transport; Legionella pneumophila; Coxiella burnetii; macrophages; protozoan; proteins

Nancy Ruddle

Professor Emeritus of and Senior Research Scientist in Epidemiology (Microbial Diseases)

Research Interests:Cell trafficking and inflammation in autoimmunity and lymphoid organ development

David Schatz

Professor of Immunobiology
Professor of Molecular Biophysics and Biochemistry

Research Interests:Biochemical mechanism and developmental regulation of V(D)J recombination and somatic hypermutation; lymphocyte development; mechanisms of DNA repair; function of the RAG1 and RAG2 proteins; mechanisms of lymphomagenesis

Mark Shlomchik

Professor of Laboratory Medicine and of Immunobiology
Associate Director, Transfusion Service

Research Interests:Autoimmunity; Blood or Blood Products or Transfusions; Bone Marrow Transplantation; Immunobiology; Immunology; Immunopathology; Immunotherapy; Lymphocytes; Transgenic Animals

Warren Shlomchik

Associate Professor of Medicine (Hematology), of Immunobiology and of Medicine (Hematology)

Research Interests:Mechanisms of antigen presentation; T cell effector function and regulation of Graft-vs.-Host Disease and Graft-vs.-Leukemia

Bing Su